There are several challenges based upon reading books based in different locations. The primary challenge I participate in is the Literary Escapes Challenge hosted by DollyCas. This intends for readers to read a book set in all 50 states plus DC and track other countries as well. Sign up here
On Goodreads there is the Around the World in 80 books which has both US Roadtrip and Global challenges. The idea being to diversify where your books are set. There is a perpetual Global one that goes by Circumnavigation. My global tracker for 2021 was Frequent Flyer which meant I could read any books in any order after starting with a US based book. There are harder and easier challenges within this global option as well. They also host some prompt based challenges called Magic Squares. Many of these prompts are different from most of the other challenges.
My Circumnavigation tracker At this point I have travelled to all 9 regions and
Frequent Flyer 2021
Here is my US Roadtrip for 2021
For a full list of challenges I found for 2022 see this blog entry.